Monoclonal Antibody to 14-3-3 Theta (Clone: ABM52H6)

Product code: 10-1058

Clonality : Monoclonal
Application : WB
Reactivity : Mouse

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Shipping Info:

2000 (throughout India)

Order now and get it on next 3-4 working days* (Major Cities)


Gene : Ywhaq
Gene ID : 22630
Uniprot ID : P68254
Alternative Name : 14-3-3 protein tau
Format : Purified
Amount : 100 µg
Clone name : ABM52H6
Isotype : Rat IgG2a, kappa
Immunogen Information : Full length recombinant protein of 14-3-3 Theta was used as the immunogen for this antibody.

14-3-3 Theta, a member of 14-3-3 family, is an adapter protein that plays an important role in a wide range of vital regulatory processes, including signal transduction, apoptosis, cell cycle progression and DNA replication. Humans have seven 14-3-3 isoforms (beta, gamma, epsilon, eta, sigma, theta and zeta) that serve as scaffolds to promote interactions of regulatory phospho-proteins involved in many vital cellular processes. 14-3-3 Theta binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif, resulting in the modulation of the activity of the binding partner except PDPK1, whose kinase activity is negatively regulated. Previous studies have shown that disturbances in native 14-3-3 levels can contribute significantly to the development of various cancers. In lung cancer biopsies, 14-3-3 Theta is found to be present in abundance.  

Purification : Protein G Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

WB: 2-4 µg/ml


Monoclonal Antibody to 14-3-3 Theta (Clone: ABM52H6)

Product code: 10-1058
mg

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