Polyclonal Antibody to 14-3-3 Zeta

Fig-1: Western blot analysis of 14-3-3 Zeta. Anti-14-3-3 Zeta antibody (11-1019) was used at 4 µg/ml on MOLT-4 lysate.

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Fig-1: Western blot analysis of 14-3-3 Zeta. Anti-14-3-3 Zeta antibody (11-1019) was used at 4 µg/ml on MOLT-4 lysate.

Product code: 11-1019

Clonality :	Polyclonal
Application :	WB
Reactivity :	Human

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Gene :	YWHAZ
Gene ID :	7534
Uniprot ID :	P63104
Alternative Name :	YWHAZ
Format :	Purified
Amount :	100 µg
Isotype :	Rabbit IgG
Immunogen Information :	A partial length recombinant 14-3-3 Zeta protein (amino acids 48-245) was used as the immunogen for this antibody.

14-3-3zeta is a central cellular hub protein regulating multiple signaling pathways involved in cancer development, progression and therapeutic resistance. It is linked to endoplasmic reticulum (ER) function in neurons, with reduced levels provoking ER stress and increasing vulnerability to excitotoxic injury. It is up-regulated in malignancy, which suggests its potential as a putative drug target for the treatment of colorectal cancer and tumorgenesis in pancreas,EOC (epithelial ovarian cancer).

Purification :	Protein A Chromatography
Content :	25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition :	Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.