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Gene : |
ATG4B |
Gene ID : |
23192 |
Uniprot ID : |
Q9Y4P1 |
Alternative Name : |
ATG4B, APG4B, AUTL1, KIAA0943 |
Format : |
Purified |
Amount : |
100 µg |
Isotype : |
Rabbit IgG |
Immunogen Information : |
A partial length recombinant APG4B protein (amino acids 150-393) was used as the immunogen for this antibody. |
APG4B (autophagy related 4B, cysteine peptidase) belongs to autophagin protein family. APG4B splits the C-terminal amino acid of ATG8 family proteins, MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. It has 393 aminoacids recidues. It has 5 isoforms produced by alternative transcriptional splicing. APG4B is mainly expressed in the skeletal muscle, brain, heart, liver and pancreas. It is a Cysteine protease needed for the cytoplasm to vacuole transport (Cvt) and autophagy. APG4B mainly expressed in the skeletal muscle, followed by brain, heart, liver and pancreas.
Western blot analysis: 4-6 µg/ml