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|
| Gene : |
ADIPOQ |
| Gene ID : |
9370 |
| Uniprot ID : |
Q15848 |
| Alternative Name : |
ADIPOQ, ACDC, ACRP30, APM1, GBP28 |
| Format : |
Purified |
| Amount : |
100 µg |
| Clone name : |
ABM52A3 |
| Isotype : |
Mouse IgG2b Kappa |
| Immunogen Information : |
A partial length recombinant protein of Adiponectin (amino acid 40-230) was used as the immunogen for this antibody. |
Syndrome, hypertension, coronary artery disease, and non-alcoholic liver disease. Adiponectin has been shown to demonstrate antitumor activity by suppressing tumor neoangiogenesis. It also contributes to carcinogenesis in obesity-related cancers. Three configurations of adiponectin have been identified and have been postulated to have distinct biological roles: LMW (Low Molecular Weight), MMW (Middle Molecular Weight) or HMW (high molecular weight). HMW adiponectin is the active form, which may specifically activate the AMPKinase signaling cascade. HMW and MMW adiponectin activate NF-κB, but LMW adiponectin does not. Clinical studies have revealed that the blood concentration of adiponectin is related to kidney injury, includes albuminuria. With the beneficial effect of adiponectin in mind, low blood adiponectin potentially serves as a biomarker for a high risk of albuminuria.
Western blot analysis: 2-4 µg/ml
