|
|
| Gene : |
ENG |
| Gene ID : |
2022 |
| Uniprot ID : |
P17813 |
| Alternative Name : |
ENG, END |
| Format : |
Purified |
| Amount : |
100 µg |
| Clone name : |
ABM46D3 |
| Isotype : |
Mouse IgG1 Kappa |
| Immunogen Information : |
A partial length recombinant Endoglin protein (amino acids 43-287) was used as the immunogen for this antibody. |
ENG (Endoglin) is an integral membrane glycoprotein that serves as a co receptor for members of the transforming growth factor-beta superfamily of proteins. It is a type I membrane glycoprotein expressed as a disulfide-linked homodimer on human vascular endothelial cells and is implicated in a dominant vascular dysplasia known as hereditary hemorrhagic telangiectasia as well as in preeclampsia. Endoglin suppresses human prostate cancer (PCa) cell invasion. It has been identified as a candidate tumor-suppressor gene in esophageal squamous cell carcinoma (ESCC).
Western blot analysis: 4-6 µg/ml
