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Gene : |
TOX3 |
Gene ID : |
27324 |
Uniprot ID : |
O15405 |
Alternative Name : |
TOX3, CAGF9, TNRC9 |
Format : |
Purified |
Amount : |
100 µg |
Clone name : |
ABM44A1 |
Isotype : |
Mouse IgG1 Kappa |
Immunogen Information : |
A partial length recombinant TOX-3 protein (amino acids 232-442) was used as the immunogen for this antibody |
TOX high mobility group box family member 3 (TOX-3) is a member of a subfamily of transcription factors that contains a High Mobility Group box (HMG-box), involved in bending and unwinding of DNA and alteration of chromatin structure. It has two transcript variants encoding different isoforms.TOX3 is expressed in estrogen receptor-positive mammary epithelial cells, including progenitor cells and highly expressed in luminal B breast cancers. Its over expression in human oligodendrocytes reduced cellular death under conditions mimicking Spinal cord injury (SCI).
Western blot analysis: 2-4 µg/ml, Immunohistochemical analysis: 5 µg/ml