|
|
Gene : |
TWISTNB |
Gene ID : |
221830 |
Uniprot ID : |
Q3B726 |
Alternative Name : |
TWISTNB |
Format : |
Purified |
Amount : |
100 µg |
Isotype : |
Rabbit IgG |
Immunogen Information : |
A partial length recombinant Twistnb protein (amino acids 28-257) was used as the immunogen for this antibody. |
Twistnb is a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors through its association with RRN3/TIF-IA may be involved in recruitment of Pol I to rDNA promoters. This protein contains 2 potential nuclear localization signals in the C terminus and shares 72% sequence identity with the mouse orthologs. Twistnb has highest expression in fetal lung, liver, and kidney, and low expression in all adult tissues.
Western blot analysis: 1-2 µg/ml