|
|
| Gene : |
UBA6 |
| Gene ID : |
55236 |
| Uniprot ID : |
A0AVT1 |
| Alternative Name : |
UBA6, MOP4, UBE1L2 |
| Format : |
Purified |
| Amount : |
100 µg |
| Isotype : |
Rabbit IgG |
| Immunogen Information : |
A partial length recombinant UBE1L2 protein (amino acids 710-955) was used as the immunogen for this antibody. |
Uba6/UBE1L2/MOP-4 is an ubiquitin-specific E1 type enzyme, homolog of the ubiquitin-activating enzyme, Uba1, which activates two ubiquitin-like proteins (UBLs), ubiquitin and FAT10. Some recent experiments suggest a testis-specific function of UBE1L2. UBE1L2 forms a thioester with FAT10 and this reaction requires the active-site cysteine of UBE1L2 and the C-terminal diglycine motif of FAT10. It can transfer ubiquitin to Ubc5 and Ubc13, suggesting its specialized role in ubiquitination reactions.
Western blot analysis: 2-4 µg/ml
