Mouse Anti Human Immature Colon Carcinoma Transcript 1(Clone:PAT1E9A)

Product code: 32-6120

Clonality : Monoclonal
Application : ELISA, WB

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Size
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20 µg


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2000 throughout India Order now and get it on next 3-4 Weeks (Major Cities)

Gene : ICT1
Gene ID : 3396
Uniprot ID : Q14197
Alternative Name : DS-1, DS1, Peptidyl-tRNA hydrolase ICT1 mitochondrial, Digestion substraction 1, Immature colon carcinoma transcript 1 protein, ICT1.
Format : Purified
Amount : 20 µg
Clone name : PAT1E9A
Isotype : Mouse IgG1 heavy chain and Kappa light chain.
Immunogen Information : Anti-human ICT1 mAb, clone PAT1E9A, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ICT1 protein 30-206 amino acids purified from E. coli.
Immature Colon Carcinoma Transcript 1 (ICT1) functions as a codon-independent translation release factor that has lost all stop codon specificity and leads the termination of translation in mitochondrion in case of abortive elongation. The mature colon epithelium has 3 differentiated cell types which arise from a multipotent stem cell. ICT1 is involved in the hydrolysis of peptidyl-tRNAs which have been prematurely terminated and consequently in the recycling of stalled mitochondrial ribosomes. Digression from the normal maturation pathway by neoplastic transformation is assumed to originate in stem cells or their early descendants.
Purification : ICT1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Content : 1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.
Storage condition : For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.


Mouse Anti Human Immature Colon Carcinoma Transcript 1(Clone:PAT1E9A)

Product code: 32-6120
mg

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