Monoclonal Antibody to Dectin-2 (Clone: ABM2H28)

Product code: 10-4013

Clonality : Monoclonal
Application : IHC, FACS, WB
Reactivity : Mouse, Human

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Shipping Info:

2000 throughout India Order now and get it on next 3-4 working days (Major Cities)

Gene : CLEC6A
Gene ID : 93978
Uniprot ID : Q6EIG7
Alternative Name : CLEC6A, CLECSF10, DECTIN2
Format : Purified
Amount : 100 µg
Clone name : ABM2H28
Isotype : Mouse IgG2 Kappa
Immunogen Information : A partial length recombinant Dectin-2 protein (amino acids 70-230) was used as the immunogen for this antibody.

Dectin-2 (C-type lectin domain family 6 member A) is a type II membrane receptor with an extracellular C-type lectin-like domain fold. Dectin-2 plays an important role in the host defense against C. albicans infection by inducing TH17 cell differentiation. It binds high-mannose carbohydrates in a Ca(2+)-dependent manner. In Dectin-2 glycosylation occurs at Asn131, Asn170. Dectin-2 has 2 isoforms produced by alternative splicing. Dectin-2 is strongly expressed in monocytes and weakly in B-cells and also expressed in spleen, tonsils, lymph node, lungs, leukocytes, dendritic cells and bone marrow.

Purification : Protein G Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Western blot analysis: 2-4 µg/ml, FACS analysis: 0.5 µg/10^6 cells, Immunohistochemical analysis: 5 µg/ml


Monoclonal Antibody to Dectin-2 (Clone: ABM2H28)

Product code: 10-4013
mg

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