|
|
Gene : |
tax |
Uniprot ID : |
P03409 |
Format : |
Purified |
Amount : |
1 mg |
Clone name : |
YRHTLV-1tax. |
Isotype : |
mouse IgG2a. |
Immunogen Information : |
r.HTLV TAX protein. |
HTLV-1 is the etiological agent for Adult T-Cell Leukemia which encodes a 40kDa cell-transforming oncoprotein called Tax. HTLV-1 Tax protein sensitizes cells to apoptotic cell death induced by DNA damaging agents. Constitutive Activation of TAK1 by HTLV-1 Tax-dependent Overexpression of TAB2 Induces Activation of JNK-ATF2 but Not IKK-NF-kB.
Direct ELISA, Western Blot, Immunoprecipitation.