|
|
| Gene : |
PAK1 |
| Gene ID : |
5058 |
| Uniprot ID : |
Q13153 |
| Alternative Name : |
Tubulin folding cofactor B, Cytoskeleton-associated
protein CKAPI, cytoskeleton associated protein 1, CKAP1, CG22, Tubulin-specific
chaperone B. |
| Format : |
Purified |
| Amount : |
20 µg |
| Clone name : |
PAT1F6ATe |
| Isotype : |
Mouse IgG2b heavy chain and k light chain. |
| Immunogen Information : |
Anti-human TBCB mAb, clone
PAT1F6AT, is derived from hybridization of mouse F0 myeloma cells with spleen
cells from BALB/c mice immunized with a recombinant human TBCB protein 1-244 amino
acids purified from E. coli. |
TBCB is a member of the Microtubules family. Biosynthesis of functional microtubules include the involvement of a number of chaperones, termed Tubulin folding cofactors A (TBCA), B (TBCB), C (TBCC), D (TBCD) and E (TBCE), which operate on folding intermediates downstream of the cytosolic chaperon, known as TCP. The 244 amino acid cytoplasmic protein TBCB has one CAP-Gly domain and is universally expressed. TBCB takes part in the regulation of tubulin heterodimer dissociation and operates as a negative regulator of axonal growth.
The antibody has been tested by ELISA, Western blot
analysis to assure specificity and reactivity. Since application varies,
however, each investigation should be titrated by the reagent to obtain optimal
results. Recommended starting dilution is 1:1500.
