|
|
| Gene : |
OTX2 |
| Gene ID : |
5015 |
| Uniprot ID : |
P32243 |
| Alternative Name : |
OTX2 |
| Format : |
Purified |
| Amount : |
100 µg |
| Isotype : |
Rabbit IgG |
| Immunogen Information : |
A partial length recombinant Otx2 protein (amino acids 1-204) was used as the immunogen for this antibody. |
Otx2 encodes a transcription factor that plays a critical role in craniofacial development and anterior brain morphogenesis. Otx2 homologs in model organisms are expressed in a complex spatial, temporal, and gradient-specific manner that is required for correct antero-posterior patterning and craniofacial development. Otx2 mutations are associated with severe ocular phenotypes and central nervous system abnormalities such as seizures, short stature and developmental delay, CPHD (Combined Pituitary Hormone Deficiency), structural abnormalities of the pituitary gland and early onset retinal dystrophy.
Western blot analysis: 2-4 µg/ml
