Monoclonal Antibody to mTLR3 (Clone: ABM24E5)

Product code: 10-3017

Clonality : Monoclonal
Application : IHC, FACS, WB
Reactivity : Mouse, Human

Shipping Info:

2000 throughout India Order now and get it on next 3-4 working days (Major Cities)

 
Size
Price

Available Pack Size(s)

18,000.00 


Bulk Order


Shipping Info:

2000 throughout India Order now and get it on next 3-4 working days (Major Cities)

Gene : Tlr3
Gene ID : 142980
Uniprot ID : Q99MB1
Alternative Name : Tlr3
Format : Purified
Amount : 100 µg
Clone name : ABM24E5
Isotype : Rat IgG2b Kappa
Immunogen Information : A partial length recombinant mTLR3 protein (amino acids 180-385) was used as the immunogen for this antibody.

Mouse Toll-like receptor 3 (mTLR3) belongs to a family of evolutionary conserved innate immune recognition molecules and recognizes double-stranded RNA, a molecular pattern associated with viral infections. It has seven exons. mTlr3 show high homology to hTLR3 in their predicted cDNA and protein sequences. The intracellular region of mTlr3 has remarkable homology with the same region of others mTlrs. mTlr3 mRNA is ubiquitously expressed in tissues, being expressed highest in spleen, kidney and lung. Its activation by the synthetic ligand polyinosine:polycytidylic acid (poly I:C) or by mRNA rapidly causes growth cone collapse and irreversibly inhibits neurite extension independent of NF-kappaB. The high levels of mTlr3 expression in Mz B cells perhaps contribute to their ability to clear antigen from the blood.

Purification : Protein G Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Western blot analysis: 2-4 µg/ml, FACS analysis: 0.5 µg/10^6 cells, Immunohistochemical analysis: 10 µg/ml


Monoclonal Antibody to mTLR3 (Clone: ABM24E5)

Product code: 10-3017
mg

Can't read the image? click here to refresh.