Monoclonal Antibody to TLR2 (Clone: ABM3A87)

Product code: 10-3026

Clonality : Monoclonal
Application : IHC, FACS, WB, IF
Reactivity : Mouse, Human

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Gene : TLR2
Gene ID : 7097
Uniprot ID : O60603
Alternative Name : TLR2, TIL4
Format : Purified
Amount : 100 µg
Clone name : ABM3A87
Isotype : Mouse IgG1 Kappa
Immunogen Information : A partial length recombinant TLR2 protein (amino acids 180-420) was used as the immunogen for this antibody.

TLR2 (Toll-Like Receptors 2) is a member of the TLR (Toll-like receptor) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLR2 forms heterodimers with TLR1 and TLR6, which is the initial step in a cascade of events leading to significant innate immune responses, development of adaptive immunity to pathogens and protection from immune sequelae related to infection with these pathogens. TLR2 also interacts with a large number of non-TLR molecules, allowing for recognition of a great number and variety of PAMPs (pathogen-associated molecular patterns). TLR2 expression has been detected in immune cells, endothelial, and epithelial cells.

Purification : Protein G Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Western blot analysis: 2-4 µg/ml, FACS analysis: 0.5 µg/10^6 cells, Immunohistochemical analysis: 5 µg/ml

1. Parida R. Human MOSPD2: A bacterial Lmb mimicked auto-antigen is involved in immune infertility. Journal of Translational Autoimmunity. 2019 Apr;100002 (1). https://doi.org/10.1016/j.jtauto.2019.100002.(Immunofluorescence)


Monoclonal Antibody to TLR2 (Clone: ABM3A87)

Product code: 10-3026
mg

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