Monoclonal Antibody to TLR3 (Clone: ABM15D5)-FITC conjugated

Product code: 10-3004-F

Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : FITC

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Shipping Info:

2000 throughout India Order now and get it on next 3-4 working days (Major Cities)

Gene : TLR3
Gene ID : 7098
Uniprot ID : O15455
Alternative Name : TLR3
Format : Purified
Amount : 100 µg
Clone name : ABM15D5
Isotype : Mouse IgG1 Kappa
Immunogen Information : A partial length recombinant TLR3 protein (amino acids 25-370) was used as the immunogen for this antibody.

TLR3 (Toll-Like Receptor-3) acts as a major receptor in virus-mediated innate immune response. This protein belongs to TLR (Toll-like receptor) family which comprises of 10-12 type I integral membrane receptor paralogs that recognize pathogen associated molecular signatures and initiate inflammatory responses. TLR3 consist of pathogen-binding ECD (Ectodomains) and cytoplasmic signaling domains, known as TIR (Toll IL-1 Receptor) domains, joined by a single transmembrane helix. TLR3 specifically senses dsRNA (Double-stranded RNA), an almost universal viral intermediate generated during most viral replications. TLR-3 activation induces multiple cellular antiviral responses, including production of IFN-alpha/beta and up-regulation of the anti-HIV cellular factor APOBEC3G. These are a family of pattern recognition receptors expressed by immune cells, including macrophages.

Purification : Protein G Chromatography
Content : 0.2 mg/ml in Tris buffer containing 0.05% Azide
Storage condition : Store the antibody at 4°C, stable for 6 months.

 FACS analysis: 0.5-1 µg/10^6 cells


Monoclonal Antibody to TLR3 (Clone: ABM15D5)-FITC conjugated

Product code: 10-3004-F
mg

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