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Alternative Name : |
Core 1 Synthase, Glycoprotein-N-Acetylgalactosamine
3-Beta-Galactosyltransferase 1, Core 1 Beta3-Gal-T1, Core 1 O-Glycan T-Synthase,
Core 1 UDP-Galactose:N-Acetylgalactosamine-Alpha-R Beta 1,3 Galactosyltransferase
1, B3Gal-T8, EC 2.4.1.122 |
Amount : |
10 µg |
Source : Escherichia Coli.
C1GALT1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 357 amino acids (30-363 a.a) and having a molecular mass of 41.4kDa.C1GALT1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Core
1 Beta3-Gal-T1 also known as, C1GALT1 creates the common core 1 O-glycan
structure, Gal-beta-1-3GalNAc-R, by the transfer of Gal from UDP-Gal to
GalNAc-alpha-1-R. Core 1 is a precursor for lots of extended mucin-type
O-glycans on cell surface
and secreted glycoproteins. Studies in mice have shown that this gene takes a
main role in angiogenesis, thrombopoiesis and kidney homeostasis.