|
|
Format : |
Purified |
Amount : |
1 mg |
Clone name : |
NYRmCD28. |
Isotype : |
Hamster IgG. |
Immunogen Information : |
Purified mouse purified mouse LN T cells. |
CD28 co-stimulation is necessary for CD4 positive T-cell proliferation & survival, interleukin-2 production, and T-helper type-2 development. Human post-thymic regulatory T cells require CD28 co-stimulation to expand and maintain potent suppressive function in vivo. Apoptosis plays a key role in the age-related decline of CD28 expression and in immunosenescence.