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|
| Gene : |
VCAM1 |
| Gene ID : |
7412 |
| Uniprot ID : |
P19320 |
| Alternative Name : |
VCAM1, L1CAM |
| Format : |
Purified |
| Amount : |
100 µg |
| Clone name : |
VCAM1/843 |
| Isotype : |
Mouse IgG1, kappa |
| Immunogen Information : |
Recombinant human VCAM1 protein |
Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses.
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
