Monoclonal Antibody to CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker)(Clone : Ber-H2)

Product code: 36-1911

Clonality : Monoclonal
Application : FACS, IF, IHC
Reactivity : Human

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2000 throughout India Order now and get it on next 3-4 weeks

Size
Price
100 µg
15,000.00 


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Shipping Info:

2000 throughout India Order now and get it on next 3-4 weeks

Gene : TNFRSF8
Gene ID : 943
Uniprot ID : P28908
Alternative Name : TNFRSF8, CD30, D1S166E
Format : Purified
Amount : 100 µg
Clone name : Ber-H2
Isotype : Mouse IgG1 Kappa
Immunogen Information : Co cell line established from a patient with Hodgkin s disease of T-cell lineage
Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. Its epitope is located between aa112-412. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkin s disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).
Purification : Affinity Chromatography
Content : 100 µg in 500 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.

Flow Cytometry (5-10ul/million cells in 0.1ml); Immunofluorescence (1:50-1:100); Immunohistology (Formalin-fixed) (1:50-1:100 for 30 minutes at RT); (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined.


Monoclonal Antibody to CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker)(Clone : Ber-H2)

Product code: 36-1911
mg

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