|
|
| Gene : |
CD44 |
| Gene ID : |
960 |
| Uniprot ID : |
P16070 |
| Alternative Name : |
CD44, LHR, MDU2, MDU3, MIC4 |
| Format : |
Purified |
| Amount : |
100 µg |
| Clone name : |
DF1485 |
| Isotype : |
Mouse IgG1, kappa |
| Immunogen Information : |
Purified CD44 antigen (PGp-1) from lymphocyte membrane |
Recognizes a cell surface glycoprotein of 80-95kDa (CD44) on lymphocytes, monocytes, and granulocytes (Leucocyte Typing Workshop V). Its epitope is resistant to digestion by trypsin and chymotrypsin. The CD44 family of glycoproteins exists in a number of variant isoforms, the most common being the standard 85-95kDa or hematopoietic variant (CD44s). Higher molecular weight isoforms are described in epithelial cells (CD44v), which are believed to function in intercellular adhesion and stromal binding. CD44 immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium.
Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml); ,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);
