Monoclonal Antibody to Cytokeratin, Basic (Type II or HMW) (Epithelial Marker)(Clone : SPM116)

Product code: 36-11108

Clonality : Monoclonal
Application : FACS, IF, WB, IHC
Reactivity : Human, Monkey, Cow, Dog, Rabbit, Mouse, Rat, Chicken

Shipping Info:

2000 throughout India Order now and get it on next 3-4 weeks

Size
Price
100 µg
15,000.00 


Bulk Order


Shipping Info:

2000 throughout India Order now and get it on next 3-4 weeks

Gene : KRT76
Gene ID : 51350
Uniprot ID : Q01546
Alternative Name : KRT76, KRT2B, KRT2P
Format : Purified
Amount : 100 µg
Clone name : SPM116
Isotype : Mouse IgG1 Kappa
Immunogen Information : Human epidermal keRatin
This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50?, 48, 46, 45, and 40kDa. This MAb recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. SPM115/SPM116 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
Purification : Affinity Chromatography
Content : 100 µg in 500 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.

Flow Cytometry (0.5-1µg/million cells in 0.1ml); Immunofluorescence (1-2µg/ml); Western Blot (0.5-1µg/ml); Immunohistology (Formalin-fixed) (0.25-0.5µg/ml for 30 min at RT); (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined.


Monoclonal Antibody to Cytokeratin, Basic (Type II or HMW) (Epithelial Marker)(Clone : SPM116)

Product code: 36-11108
mg

Can't read the image? click here to refresh.