Monoclonal Antibody to Insulin / IRDN (beta-Cell & Insulinoma Marker)(Clone : SPM531)

Product code: 36-1311

Clonality : Monoclonal
Application : FACS, IF, IHC
Reactivity : Human, Bovine, Pig, Rabbit, Rat

Shipping Info:

2000 throughout India Order now and get it on next 3-4 weeks

Size
Price
100 µg


Shipping Info:

2000 throughout India Order now and get it on next 3-4 weeks

Gene : INS
Gene ID : 3630
Uniprot ID : P01308
Alternative Name : INS
Format : Purified
Amount : 100 µg
Clone name : SPM531
Isotype : Mouse IgG1 Kappa
Immunogen Information : Full length (1-84 amino acid) purified pig insulin, conjµgated to KLH
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
Purification : Affinity Chromatography
Content : 100 µg in 500 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.

Flow Cytometry (0.5-1µg/million cells in 0.1ml); Immunofluorescence (1-2µg/ml); Immunohistology (Formalin-fixed) (0.5-1µg/ml for 30 minutes at RT); (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined.


Monoclonal Antibody to Insulin / IRDN (beta-Cell & Insulinoma Marker)(Clone : SPM531)

Product code: 36-1311
mg

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