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|
Gene : |
MUC1 |
Gene ID : |
4582 |
Uniprot ID : |
P15941 |
Alternative Name : |
MUC1, PUM |
Format : |
Purified |
Amount : |
100 µg |
Clone name : |
MUC1/520 |
Isotype : |
Mouse IgG2a, lambda |
Immunogen Information : |
Human milk-fat globule membranes (HMFGM) |
In Western blotting, it recognizes proteins in MW range of 265-400kDa, identified as different glycoforms of EMA. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. In immunohistochemical assays, it superbly stains routine formalin/paraffin carcinomas. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.
Immunohistology (Formalin-fixed) (0.5-1.0ug/ml for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),