Monoclonal Antibody to MUC18 / CD146 / MCAM (Melanoma Cell Adhesion Molecule)(Clone : MUC18/1130)

Product code: 36-1419

Clonality : Monoclonal
Application : FACS, IF, IHC
Reactivity : Human

Shipping Info:

2000 throughout India Order now and get it on next 3-4 weeks

Size
Price
100 µg
15,000.00 


Bulk Order


Shipping Info:

2000 throughout India Order now and get it on next 3-4 weeks

Gene : MCAM
Gene ID : 4162
Uniprot ID : P43121
Alternative Name : MCAM, MUC18
Format : Purified
Amount : 100 µg
Clone name : MUC18/1130
Isotype : Mouse IgG1 Kappa
Immunogen Information : Recombinant human MUC18 protein
The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Purification : Affinity Chromatography
Content : 100 µg in 500 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.

Flow Cytometry (0.5-1µg/million cells in 0.1ml); Immunofluorescence (0.5-1.0µg/ml); Immunohistology (Formalin-fixed) (0.5-1.0µg/ml for 30 minutes at RT); (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined.


Monoclonal Antibody to MUC18 / CD146 / MCAM (Melanoma Cell Adhesion Molecule)(Clone : MUC18/1130)

Product code: 36-1419
mg

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