Monoclonal antibody to MyD88 (Clone: ABM2H20)

Product code: 10-3012-F

Clonality : Monoclonal
Application : FACS
Conjugate : FITC
Reactivity : Human

Shipping Info:

2000 throughout India Order now and get it on next 3-4 working days (Major Cities)

 
Size
Price

Available Pack Size(s)

18,000.00 


Bulk Order


Shipping Info:

2000 throughout India Order now and get it on next 3-4 working days (Major Cities)

Gene : MYD88
Gene ID : 4615
Uniprot ID : Q99836
Format : Purified
Amount : 100 µg
Clone name : ABM2H20
Isotype : Mouse IgG1 Kappa
Immunogen Information : A partial length recombinant protein of human MyD88 (amino acids 13-221) was used as an immunogen for this antibody.

MyD88 (Myeloid differentiation factor) is an essential adaptor molecule in all TLR (Toll-like receptor) signaling pathways except TLR3. MyD88 is composed of an N-terminal (Death Domain) and a highly conserved C-terminal TIR (Toll/interleukin-1 Receptor) domain. It is found to stimulate IL-1R/IL18R-mediated signaling. MyD88-dependent signaling is also important in the regulation of innate as well as acquired immunity, in particular, T-cell responses, to various microbial pathogens. After activation of TLRs, MyD88 is phosphorylated and subsequently recruits IRAKs (IL-1R Associated Kinases) and other downstream proteins such as TRAF6, finally resulting in activation of the NF-kappaB (nuclear factor kappa B) pathway.

Purification : Protein G Chromatography
Content : 0.2 mg/ ml of Tris buffer containing 0.05% sodium azide.
Storage condition : Store the antibody at 4°C; stable for 6 months.

 FACS Analysis: 0.5-1 µg/ml


Monoclonal antibody to MyD88 (Clone: ABM2H20)

Product code: 10-3012-F
mg

Can't read the image? click here to refresh.