Monoclonal Antibody to PAX6 (Stem Cell Marker)(Clone : PAX6/498)

Product code: 36-1527

Clonality : Monoclonal
Application : IF, WB, FACS
Reactivity : Human, Mouse, Rat, Chicken

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2000 throughout India Order now and get it on next 3-4 weeks

Size
Price
100 µg


Shipping Info:

2000 throughout India Order now and get it on next 3-4 weeks

Gene : PAX6
Gene ID : 5080
Uniprot ID : P26367
Alternative Name : PAX6, AN2
Format : Purified
Amount : 100 µg
Clone name : PAX6/498
Isotype : Mouse IgG1 Kappa
Immunogen Information : Recombinant fragment (N-terminus; aa 1-300) of human PAX6 protein
Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
Purification : Affinity Chromatography
Content : 100 µg in 500 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.

Flow Cytometry (0.5-1µg/million cells in 0.1ml); Immunofluorescence (0.5-1µg/ml); Western Blot (0.5-1µg/ml); Optimal dilution for a specific application should be determined.


Monoclonal Antibody to PAX6 (Stem Cell Marker)(Clone : PAX6/498)

Product code: 36-1527
mg

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