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|
Gene : |
PAX7 |
Gene ID : |
5081 |
Uniprot ID : |
P23759 |
Alternative Name : |
PAX7, HUP1 |
Format : |
Purified |
Amount : |
100 µg |
Clone name : |
PAX7/497 |
Isotype : |
Mouse IgG1, kappa |
Immunogen Information : |
Recombinant fragment (aa300-600) of human PAX7 protein |
The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).
Immunofluorescence (1-2ug/ml); Flow Cytometry (1-2ug/million cells); Western Blot (1-2ug/ml);