|
|
| Gene : |
PGR |
| Gene ID : |
5241 |
| Uniprot ID : |
P06401 |
| Alternative Name : |
PGR, NR3C3 |
| Format : |
Purified |
| Amount : |
100 µg |
| Clone name : |
PR500 |
| Isotype : |
Mouse IgG1, kappa |
| Immunogen Information : |
Recombinant human Progesterone Receptor protein |
This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone.
Immunohistochemistry (Formalin-fixed) (1-2ug/ml) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);
