|
|
| Gene : |
PRLR |
| Gene ID : |
5618 |
| Uniprot ID : |
P16471 |
| Alternative Name : |
PRLR |
| Format : |
Purified |
| Amount : |
100 µg |
| Clone name : |
B6.2 |
| Isotype : |
Mouse IgG1, kappa |
| Immunogen Information : |
Semi-purified human prolactin receptor |
It recognizes a protein of 70kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.
Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml); ,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);
