|
|
| Gene : |
TLR8 |
| Gene ID : |
51311 |
| Uniprot ID : |
Q9NR97 |
| Alternative Name : |
TLR8, UNQ249/PRO286 |
| Format : |
Azide Free,Purified |
| Amount : |
100 µg |
| Clone name : |
ABM15F6 |
| Isotype : |
Mouse IgG1 Kappa |
| Immunogen Information : |
A partial length recombinant TLR8 protein (amino acids 750-900) was used as the immunogen for this antibody. |
Toll like receptor 8, also known as CD288, is a member of TLR family. It plays an important role in sensing phagocytosed pathogen. TLR8 recognizes ssRNA and recruits MyD88 and leads to the activation of transcription factor NF-kappa B. TLR8 TLR8 has two splice variants, viz., TLR8v1 and TLR8v2 and one missense variant, termed G or A1G allele of TLR8. TLR8v1 has additional 19 amino acids in the N-terminus. It is predominantly expressed in lung and peripheral blood leukocytes.
Immunohistochemical analysis: 5 µg/ml;FACS analysis: 2 µg/10^6 cells
