Mouse Anti Human CASP8 and FADD-like apoptosis regulator(Clone:P5D8AT.)

Product code: 32-6060

Clonality : Monoclonal
Application : ELISA, WB

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Size
Price
20 µg
16,150.00 


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Shipping Info:

2000 throughout India Order now and get it on next 3-4 Weeks (Major Cities)

Gene : CFLAR
Gene ID : 8837
Uniprot ID : O15519
Alternative Name : CASP8 and FADD-like apoptosis regulator, Cellular FLICE-like inhibitory protein, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, MACH-related inducer of toxicity, Caspase homolog, Inhibitor of FLICE, FADD-like antiapoptotic
Format : Purified
Amount : 20 µg
Clone name : P5D8AT.
Isotype : Mouse IgG3 heavy chain and ? light chain.
Immunogen Information : Anti-human CFLAR mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CFLAR amino acids 1-376 purified from E. coli.
CFLAR contains two death effector domains (DEDs) and a caspase-like domain. CFLAR may play a critical role between cell survival and cell death pathway in mammalian cells. CFLAR also interacts with adapter protein FADD and caspase-8 and -10, and potently inhibits apoptosis induced by all known death receptors DR3 (death receptor 3), TRAIL-R (TNF-related apoptosis-inducing ligand receptor) and TNFR1 (tumor necrosis factor receptor 1).
Purification : CFLAR antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Content : 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Storage condition : For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

CFLAR antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1,000. Recommended starting dilution is 1:500.


Mouse Anti Human CASP8 and FADD-like apoptosis regulator(Clone:P5D8AT.)

Product code: 32-6060
mg

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