|
|
Gene : |
CSF2 |
Gene ID : |
1437 |
Uniprot ID : |
P04141 |
Alternative Name : |
CSF-2, MGI-1GM, GM-CSF, Pluripoietin-alpha, Molgramostin, Sargramostim, MGC131935, MGC138897. |
Format : |
Purified |
Amount : |
1 mg |
Clone name : |
NYRhGMCSF. |
Isotype : |
Mouse IgG. |
Immunogen Information : |
r.Human GM-CSF. |
GMCSF is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13.GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
Direct ELISA, Western Blot, Immuneprecipitation.