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Gene : |
REXO2 |
Gene ID : |
25996 |
Uniprot ID : |
Q9Y3B8 |
Alternative Name : |
REX2, RNA exonuclease 2 homolog (S. cerevisiae), CGI-114, RFN, SFN, Oligoribonuclease, mitochondrial, RNA exonuclease 2 homolog, Small fragment nuclease,REXO2, SMFN. |
Format : |
Purified |
Amount : |
20 µg |
Clone name : |
PAT59D9Ae |
Isotype : |
Mouse IgG2b heavy chain and Kappa light chain. |
Immunogen Information : |
Anti-human REXO2 mAb, clone PAT59D9A, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human REXO2 protein 26-237 amino acids purified from E. coli. |
EXO2 is a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. RNA Exonuclease 2 (REXO2) takes part in DNA repair, replication, and recombination, and in RNA processing and degradation. EXO2 is involved in resistance of human cells to UV-C-induced cell death via its part in the DNA repair process.
The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:500.