|
|
| Gene : |
SGCD |
| Gene ID : |
6444 |
| Uniprot ID : |
Q92629 |
| Alternative Name : |
35DAG, CMD1L, DAGD, SG-delta, SGCDP, SGD,
Delta-sarcoglycan, 35 kDa dystrophin-associated glycoprotein. |
| Format : |
Purified |
| Amount : |
20 µg |
| Clone name : |
PAT19G8AT |
| Isotype : |
MouseIgG1 heavy chain and k light chain. |
| Immunogen Information : |
Anti-human SGCD mAb, clone PAT19G8AT,
is derived from hybridization of mouse F0 myeloma cells with spleen cells from
BALB/c mice immunized with a recombinant human SGCD protein 57-289 amino
acids purified from E. coli. |
Sarcoglycan Delta (SGCD) is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC) and is expressed mainly in skeletal and cardiac muscle. DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. SGCD proteins mutations have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. SGCD gene expression is regulated by MITF In melanocytic cells.
The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.
