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Gene : |
TPD52L1 |
Gene ID : |
7164 |
Uniprot ID : |
Q16890 |
Alternative Name : |
Tumor protein D53, Tumor protein D52-like 1, TPD52L1, hD53, D53, MGC8556, TPD52L2. |
Format : |
Purified |
Amount : |
20 µg |
Clone name : |
Pd1C5AT. |
Isotype : |
Mouse IgG2b heavy chain and ? light chain. |
Immunogen Information : |
Anti-human TPD52L1 mAb, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TPD52L1 amino acids 1-131 purified from E. coli. |
TPD52L1 (hD53, hD53L1) is a member of D52 gene family and overexpressed in human breast carcinoma. TPD52L1 contains coiled-coil motif, which is responsible for homo- and heteromeric interaction, and may be a regulator of cell proliferation and calcium-mediated signal transduction. Moreover, TPD52L1 interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis.
TPD52L1 antibody has been tested by ELISA, Western blot and immunohistochemistry analysis to assure specificity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1:3,000. Recommended starting dilution is 1:1000.