Polyclonal Antibody to DEPTOR/DEPDC6

Product code: 11-1021

Clonality : Polyclonal
Application : WB
Reactivity : Human

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Gene : DEPTOR
Gene ID : 64798
Uniprot ID : Q8TB45
Alternative Name : DEPTOR, DEPDC6
Format : Purified
Amount : 100 µg
Isotype : Rabbit IgG
Immunogen Information : A partial length recombinant DEPTOR protein (amino acids 111-301) was used as the immunogen for this antibody.
DEPTOR is an mTOR inhibitor whose expression is negatively regulated by mTOR. DEPTOR expression is required to maintain PI3K and Akt activation and to inhibit apoptosis. DEPTOR is expressed in different microvascular ECs (endothelial cells). It plays a key role in maintaining stem cell pluripotency by limiting mTOR activity in undifferentiated embryonic stem cells (ESCs). It is overexpressed in RPMI-8226 human multiple myeloma cells, and plays an important role in maintaining cell survival.
Purification : Protein A Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.

Western blot analysis: 2-4 µg/ml


Polyclonal Antibody to DEPTOR/DEPDC6

Product code: 11-1021
mg

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