Polyclonal Antibody to POU3F2

Product code: 11-12016

Clonality : Polyclonal
Application : WB
Reactivity : Human

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Gene : POU3F2
Gene ID : 5454
Uniprot ID : P20265
Alternative Name : POU3F2, BRN2, OCT7, OTF7
Format : Purified
Amount : 100 µg
Isotype : Rabbit IgG
Immunogen Information : A partial length recombinant POU3F2 protein (amino acids 220-421) was used as the immunogen for this antibody.

POU3F2 is a developmental neural cell-specific POU domain transcription factor and is crucial for cell lineage determination. In melanoma lesions, cells expressing high levels of POU3F2 show enhanced invasive and metastatic capacity that can in part be explained by repression of MITF (Micropthalmia-associated Transcription Factor) expression via POU3F2 binding to its promoter.�POU3F2 is expressed exclusively in the central nervous system, more specifically in postmitotic neurons and glia.

Purification : Protein A Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.

Western blot analysis: 1-2 µg/ml


Polyclonal Antibody to POU3F2

Product code: 11-12016
mg

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