|
|
| Gene : |
S1PR3 |
| Gene ID : |
1903 |
| Uniprot ID : |
Q99500 |
| Alternative Name : |
S1PR3, EDG3 |
| Format : |
Purified |
| Amount : |
100 µg |
| Isotype : |
Rabbit IgG |
| Immunogen Information : |
A partial length recombinant S1P3 receptor, Edg-3 protein (amino acids 80-350) was used as the immunogen for this antibody. |
S1PR3 (sphingosine-1–phosphate receptor–3) is a vascular barrier–regulatory member of the S1P family of receptors (S1PR1–5) and a critical signaling molecule mediating cell proliferation, adhesion, angiogenesis, and vascular permeability. In a nitrated form protein in plasma it is found as a biomarker in patients with ALI (acute lung injury). S1PR3 plays an important role in promoting pulmonary inflammation, disrupting cell-cell junctions, and increasing lung permeability and alveolar flooding during inflammation.
Western blot analysis: 2-4 µg/ml
