Polyclonal Antibody to SPZ1/TSP1

Product code: 11-12019

Clonality : Polyclonal
Application : WB
Reactivity : Human

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Gene : SPZ1
Gene ID : 84654
Uniprot ID : Q9BXG8
Alternative Name : SPZ1, TSP1
Format : Purified
Amount : 100 µg
Isotype : Rabbit IgG
Immunogen Information : A partial length recombinant SPZ1/TSP1 protein (amino acids 10-213) was used as the immunogen for this antibody.

Spz1, a bHLH-zip protein, acts as a proto-oncogene regulated by a MAPK signaling pathway that can increase cell proliferation and tumorigenic activity as well as leading to primary tumor formation (15899793). It is expressed specifically in the testis and epididymis (11165476). Spz1 is a specific binding partner of the gamma2 catalytic subunit of Phosphatase-1c-gamma (PP1c-gamma). The interaction between Spz1 and PP1cgamma2 may be required for proper regulation of spermatogenesis and fertility in males.

Purification : Protein A Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.

Western blot analysis: 1-2 µg/ml


Polyclonal Antibody to SPZ1/TSP1

Product code: 11-12019
mg

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