Polyclonal Antibody to TLR1

Product code: 11-3041

Clonality : Polyclonal
Application : WB
Reactivity : Mouse, Human

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Gene : TLR1
Gene ID : 7096
Uniprot ID : Q15399
Alternative Name : TLR1, KIAA0012
Format : Purified
Amount : 100 µg
Isotype : Rabbit IgG
Immunogen Information : A partial length recombinant TLR1 protein (amino acids 300-500) was used as the immunogen for this antibody.
Toll/interleukin-1 receptor-like protein (TLR1) is a member of the Toll-like receptor (TLR) family which has close similarity to Drosophila Toll homologs. Toll receptors are involved in mediating dorsoventral polarization in the developing Drosophila embryo. TLR1 is a type I transmembrane receptor that characteristically contains an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLRs generally exist as homodimers but TLR6 forms heterodimers with TLR2 and binds lipopeptide components of gram-positive and gram-negative bacterial cell walls. TLR1 is found to be involved in ocular toxoplasmosis, and leprosy. It is highly expressed in spleen, ovary, peripheral blood leukocytes, thymus and small intestine.
Purification : Protein A Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Western blot analysis: 4-6 µg/ml


Polyclonal Antibody to TLR1

Product code: 11-3041
mg

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