|
|
| Gene : |
ITGAL |
| Gene ID : |
3683 |
| Uniprot ID : |
P20701 |
| Alternative Name : |
Integrin, alpha L, CD11A, p180, alpha polypeptide, ITGAL, LFA-1, LFA1A
TypeRat Anti Mouse Monoclonal. |
| Format : |
Purified |
| Amount : |
1 mg |
| Clone name : |
mCD11a. |
| Isotype : |
Rat IgG2b. |
| Immunogen Information : |
Enriched mouse peritoneal macrophages. |
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling.
