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| Alternative Name : |
Tubulin folding cofactor C, tubulin-specific chaperone c, Tubulin-folding cofactor C, CFC. |
| Amount : |
10 µg |
Source : E.coli.
TBCC Human Recombinant produced in E. coli is a single polypeptide chain containing 369 amino acids (1-346) and having a molecular mass of 41.7 kDa.TBCC is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Tubulin folding cofactor C (TBCC) is a member of the TBCC family. TBCC has a role in the control of centrosome and Golgi apparatus positioning, with effects on cell shape and cell migration. Cofactor C is 1 of 4 proteins (cofactors A,D,E and C) engaged in the pathway leading to properly folded b-tubulin from folding intermediates. Cofactor E attaches to the cofactor D/beta-tubulin complex; their interaction with cofactor C subsequently causes the release of beta-tubulin polypeptides which are bound to the native state.
