|
|
Gene : |
PLIN2 |
Gene ID : |
123 |
Uniprot ID : |
Q99541 |
Alternative Name : |
PLIN2, ADFP |
Format : |
Purified |
Amount : |
100 µg |
Clone name : |
ABM4A83 |
Isotype : |
Mouse IgG2b Kappa |
Immunogen Information : |
A partial length recombinant human Adipophilin protein (amino acids 210-421) was used as the immunogen for this antibody. |
Adipophilin (ADPH) or adipose differentiation-related protein (ADRP), is a member of the perilipin family of cytoplasmic lipid droplet (CLD)-binding proteins which was initially described in adipocytes and is considered a marker of lipid accumulation. It is a 50-kDa protein that is crucially dependent on triglyceride synthesis for stability. Adipophilin is found in many mammalian cell types, including hepatocytes, adipocytes, muscle cells, and mammary epithelial cells, either during development or in the mature functioning cell. Adipophilin is found associated with intracellular lipid droplets in a variety of cells and tissues that store or synthesize lipids. ADPH functions in lipid storage droplets (LSD) formation, fatty acid uptake, and milk lipid secretion; however, little is known about the structural or biochemical properties involved in its association with LSDs or how it accomplishes its biological functions.
Western blot analysis: 2-4 µg/ml