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|
| Gene : |
HPRT1 |
| Gene ID : |
3251 |
| Uniprot ID : |
P00492 |
| Alternative Name : |
Hypoxanthine-Guanine Phosphoribosyltransferase, EC 2.4.2.8, HGPRT, HGPRTase, HPRT, HPRT1. |
| Format : |
Purified |
| Amount : |
20 µg |
| Clone name : |
PAT2G8AT. |
| Isotype : |
Mouse IgG1 heavy chain and k light chain. |
| Immunogen Information : |
Anti-human HPRT mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human HPRT amino acids 1-218 purified from E. coli. |
HPRT1 has a main part in the generation of purine nucleotides through the purine salvage pathway. HPRT1 primarily functions to salvage purines from degraded DNA to renewed purine synthesis. Therefore, it performs as a catalyst in the reaction between guanine and phosphoribosyl pyrophosphate to form GMP.
HPRT antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500~1:5000.Recommended starting dilution is 1:1000.
