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|
Gene : |
IL2 |
Gene ID : |
3558 |
Uniprot ID : |
P60568 |
Alternative Name : |
T-cell growth factor (TCGF), Aldesleukin, Lymphokine, IL-2. |
Format : |
Purified |
Amount : |
1 mg |
Clone name : |
NYRmIL-2. |
Isotype : |
Rat IgG2a. |
Immunogen Information : |
r.Murine IL-2. |
IL2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.