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| Alternative Name : |
Melanoregulin, DSU, Dilute Suppressor Protein Homolog, WDT2,
Whn-Dependent Transcript 2. |
| Amount : |
10 µg |
Source : Escherichia Coli.
MREG Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 237 amino acids (1-214 a.a) and
having a molecular mass of 27.3kDa.MREG is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Melanoregulin
(MREG) takes part in membrane fusion and in regulating the biogenesis of disk
membranes of photoreceptor rods. MREG is expressed in photoreceptor cells as
two isoforms as a result of alternative splicing. MREG interacts with
Peripherin-2, a photoreceptor specific tetraspanin protein which is required to
preserve normal cell structure during the renewal process of membrane fusion.
Moreover, MREG plays a part in the incorporation of pigments into hair.
