Polyclonal Antibody to APG16L

Product code: 11-10020

Clonality : Polyclonal
Application : WB
Reactivity : Human

Shipping Info:

2000 throughout India Order now and get it on next 3-4 working days (Major Cities)

 
Size
Price

Available Pack Size(s)

15,000.00 


Bulk Order


Shipping Info:

2000 throughout India Order now and get it on next 3-4 working days (Major Cities)

Gene : ATG16L1
Gene ID : 55054
Uniprot ID : Q676U5
Alternative Name : ATG16L1, APG16L, UNQ9393/PRO34307
Format : Purified
Amount : 100 µg
Isotype : Rabbit IgG
Immunogen Information : A partial length recombinant APG16L protein (amino acids 35-260) was used as the immunogen for this antibody.
ATG16L1/APG16L is part of a large protein complex that functions as a molecular scaffold mediating protein-protein interactions necessary for formation of the autophagosome in response to both classical and pathogen-related autophagy stimuli. APG16L protein contains an N-terminal Atg5-binding domain, a coiled-coil domain and a C-terminal WD (tryptophan-aspartic acid)-repeat domain. APG16L forms a complex with the Atg12Atg5 conjugate and together they are actively translocated to the phagophore and are further elongated during autophagosome formation. Genetic variation in the APG16L gene has been recently implicated in Crohn's disease pathogenesis. Polymorphism within APG16L gene results in excessive production of IL-1beta and IL-6 culmunating in the inflammatory process in Crohn's disease.
Purification : Protein A Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Western blot analysis: 2-4 µg/ml


Polyclonal Antibody to APG16L

Product code: 11-10020
mg

Can't read the image? click here to refresh.