Monoclonal Antibody to ClEC9A (Clone: ABM23H8)

Product code: 10-4020

Clonality : Monoclonal
Application : WB
Reactivity : Human

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Shipping Info:

2000 (throughout India)

Order now and get it on next 3-4 working days* (Major Cities)


Gene : CLEC9A
Gene ID : 283420
Uniprot ID : Q6UXN8
Alternative Name : C-type lectin domain family 9 member A, CLEC9A
Format : Purified
Amount : 100 µg
Clone name : ABM23H8
Isotype : Mouse IgG1, Kappa
Immunogen Information : A partial length recombinant protein ( a.a 15-218) of CLEC9A was used as the immunogen for this antibody.

CLEC9A is a C-type lectin receptor involved in the sensing and presentation of antigens derived from necrotic cells. It is expressed on the surface of the mouse and human dendritic cell subsets specialized for the uptake and processing of material from dead cells. CLEC9A is expressed at the cell surface as a glycosylated dimer and can mediate endocytosis, but not phagocytosis. It possesses a cytoplasmic immunoreceptor tyrosine-based activation-like motif that can recruit Syk kinase and can induce proinflammatory cytokine production. CLEC9A provides targeted recruitment of the adaptive immune system during infection and can also be utilized to enhance immune responses generated by vaccines.

Purification : Protein G Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

WB: 2-4 µg/ml


Monoclonal Antibody to ClEC9A (Clone: ABM23H8)

Product code: 10-4020
mg

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