|
|
| Gene : |
KLF7 |
| Gene ID : |
8609 |
| Uniprot ID : |
O75840 |
| Alternative Name : |
UKLF, Krueppel-like factor 7, Ubiquitous krueppel-like factor, KLF7. |
| Format : |
Purified |
| Amount : |
20 µg |
| Clone name : |
PAT3G3A |
| Isotype : |
Mouse IgG1 heavy chain and Kappa light chain. |
| Immunogen Information : |
Anti-human KLF7 mAb, clone PAT3G3A, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human KLF7 protein 1-302 amino acids purified from E. coli. |
Kruppel-Like Factor 7 (KLF7) is a part of the Kruppel-like transcriptional regulator family whose members regulate cell proliferation, differentiation and survival and contain 3 C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. KLF7 contributes to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and also by deregulating adipocytokine secretion in adipocytes.
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.
